GLB-13 is associated with oxidative stress resistance incaenorhabditis elegans
نویسندگان
چکیده
منابع مشابه
Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress
A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects of glucose are poorly understood. Here we establish a causative relationship between endogenous glucose storage in the form of glycogen, resistance to oxidative stress and organismal aging in Caenorhabditis elegans. We find that glycogen ...
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One cellular mechanism thought to be particularly important as a constraint on lifespan and life-history strategies is oxidative stress. Susceptibility to oxidative stress is influenced by a number of antioxidant defences, whose effectiveness depends on the synergistic and competitive interactions among them (biochemical integration). It is generally assumed that exposure to oxidative stress is...
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ژورنال
عنوان ژورنال: IUBMB Life
سال: 2013
ISSN: 1521-6543
DOI: 10.1002/iub.1132